DEVELOPMENT AND CHARACTERIZATION OF REVERSE GENETICS SYSTEMS OF FELINE INFECTIOUS PERITONITIS VIRUS FOR ANTIVIRAL RESEARCH

Development and characterization of reverse genetics systems of feline infectious peritonitis virus for antiviral research

Abstract Feline infectious peritonitis (FIP) is a lethal, immune-mediated disease in cats caused by feline infectious peritonitis virus (FIPV), a biotype of feline coronavirus (FCoV).In contrast to feline enteric coronavirus (FECV), which exclusively infects enterocytes and causes diarrhea, FIPV specifically targets macrophages, resulting in the de

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Synthesizing fatal crashes involving partially automated vehicles and comparing with fatal crashes involving non-automated vehicles

Automated vehicles (AVs) are expected to improve safety by gradually reducing human decisions while driving.However, there are still questions on their effectiveness as we transition from almost 0% AVs to 100% AVs with different levels of vehicle autonomy.The focus of this study, therefore, is on synthesizing and identifying risk factors influencin

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